Penn State was dominated in all facets of the game en route to a 15-7 loss to Johns Hopkins on Saturday at Panzer Stadium.
According to a report by NFL Network's Tom Pelissero, Wade signed with Pittsburgh in the minutes following the draft.
Fries is the second Nittany Lion offensive lineman selected in the 2021 NFL Draft.
Menet was snagged in the seventh round of the NFL Draft.
Toney was drafted in the seventh of this year's draft, making him the fourth Nittany Lion off the board thus far.
The Nittany Lions weathered a first half storm to advance to the Sweet 16.