The crew will be live on the air on Old Main Lawn this Saturday at 9 a.m.
The Nittany Lions fell 10 spots in the poll after a disappointing last week on the pitch.
College GameDay last returned to State College a season ago for the loss against Ohio State.
The last time College GameDay came to Old Main was for the 2021 White Out against Auburn.
The Nittany Lions began the season as the No. 2 team in the land, but have since fallen to No. 13, its lowest ranking to date this year.
The announcement comes during the same week Penn State is rumored to switch to Adidas.