Owusu joins the Nittany Lions as a transfer from Virginia Tech.
Isaac's stat line this season is impressive, totaling 12 tackles and five sacks through the Nittany Lions' first five games this season.
In his first start with the Panthers, Christian Veilleux led Pitt to a 38-21 upset win over Louisville.
Parsons registered four solo tackles, three tackles for loss, two sacks, a forced fumble, and a fumble recovery.