The Nittany Lions outshot Clarkson 81-48.
UMass is 1-6 this season, with its lone win being a 41-30 victory over New Mexico State.
The Nittany Lions have dominated in the secondary, holding some of the best passing statistics in the nation.
"I've grown up wanting to play for this program, so to finally throw the jersey on and be able to score in the first period was unreal."
Penn State still doesn't have a protected rival within the 18-team conference.