The Nittany Lions fell short during a marathon shootout in their trip to the Frozen Confines.
The game featured 14 lead changes and 11 ties.
The freshman underwent heart surgery on November 22 and has been recovering at home.
The game was tied at 55 going into the fourth quarter.
The Nittany Lions gain two more points in latest AP Poll.
The Nittany Lions outscored the Quakers 52-35 in the second half.