Niederhauser was the Nittany Lions' first portal commit from the current cycle.
Owusu was the first Lady Lion drafted since Maggie Lucas in 2014.
The Nittany Lions blew a 8-0 lead in game two of the series.
Head coach Clarisa Crowell earned her 100th win at Penn State in game two.
The Nittany Lions head into the EIVA Tournament next week on an eight-game winning streak.
Penn State moved to 2-2 in the Big Ten.