The Nittany Lions' six-run second inning was overcome by a fired-up River Hawks squad.
Penn State is now 3-0 at home.
Clutch hits from the Nittany Lions earned them the second win of the Penn State Softball Invitational.
With UCLA and USC departing the Pac-12, four Big Ten institutions will have varsity men's volleyball programs starting next year.
"Here we are playing in the second round and expected to win. I think a lot of people didn't think we'd win any games."
The Nittany Lions season is likely over.