The Nittany Lions outshot Clarkson 81-48.
A 73rd minute go-ahead goal from captain Peter Mangione was the difference as the Nittany Lions gave Northwestern its first loss.
Sophia Gladieux scored two goals for her fourth multi-goal game of the season.
The game marked just the third time that the Nittany Lions drew the Boilermakers.
Wolfe has registered three starts and 10 appearances so far for a Nittany high-performing Lion backline.
$1.50 of every State Light case purchase will go directly to Happy Valley United.