Heising has 74 goals, 63 assists, and 147 points across her 155 career games, all of which are program highs.
"Penn State is a special place," Gerber wrote. "Thanks for four memorable years, Penn State Athletics."
Biro is called up to the main roster after two brief stints on the Sabres' taxi squad earlier this season.
Mack was tragically killed in a car crash on July 24, 2021, in the suburbs of Minneapolis, Minn., at just 20 years old.
"We believe Makenna is one of the best guards in the country, and we don't think she's getting the recognition she deserves."
A three-minute scoreless streak in the second half put the nail in the coffin for Micah Shrewsberry's squad.