A solid performance from freshman goaltender Noah Grannan and an electric offense kept Penn State undefeated two games into the season.
After tying up the game in the third period, the Nittany Lions let up a late goal that proved to be the difference in Saturday's contest.
Penn State's new transfers, Ashton Calder and Ture Linden, were instrumental in the team's 5-2 defeat of Canisius.
The Nittany Lions dropped their third conference matchup of the season Friday night against Ohio State.
A four-goal first half, with two from Liam Butts, was all the Nittany Lions needed, as they breezed past the Spartans.
The win ended a four-year losing streak to the Hawkeyes.