Matt Traynor tallied six goals in the Nittany Lions' dominant outing.
Sanderson has a record of 200-16-2 as Penn State's head coach.
The win gave Cael Sanderson his 200th as the head coach of the Nittany Lions.
The Golden Gophers' two early first-period goals doomed the Nittany Lions from the start.
Boston College is O'Brien's fifth job since leaving Penn State in 2013.
Amid transfers and incoming freshmen, Penn State softball has its eyes set on regionals.