Freiermuth will get season-ending surgery to deal with an injury he suffered against Ohio State.
Penn State falls to 0-5 for the first time in program history.
Levis was named the starting signal-caller just minutes before the Nittany Lions' week five contest.
You have the chance to see your face in the stands of Pegula Ice Arena this winter.
Penn State is a one-point home underdog against the Hawkeyes.
Its closure will begin on Sunday, November 22, and last until an unspecified date next year.