The Nittany Lions fell after reaching their first Elite Eight game since 2018.
The Nittany Lions had 586 offensive yards and five touchdowns against the Spartans.
After a long season of disappointments, Penn State's running backs finally figured it out.
The Nittany Lions recorded seven sacks and 12 tackles for loss during Friday's dominant victory.
Following the sweep, the Nittany Lions' regular season is over, and they will await selection for the NCAA Tournament.