The Nittany Lions earned the much needed sweep thanks to a 16 kill performance from Kennedy Martin.
It was the team's third contest this season that was decided in overtime.
It's the first time Penn State has moved from the second spot all season.
College GameDay last returned to State College a season ago for the loss against Ohio State.
The Nittany Lions finish strong to start the Penn State Classic.
Penn State quickly lost control against the Hoosiers despite Kai Phillips' early goal.