The Nittany Lions went 5-31 at the plate in the final game of the series.
The Nittany Lions are the lowest-seeded team in the NCAA Tournament.
Penn State broke its single-season record with 291 runs scored on Friday.
Penn State dropped their second straight game.
The Nittany Lions have won three consecutive EIVA titles.
The Nittany Lions punched their ticket to Ann Arbor for the Big Ten Tournament semifinals.