The Nittany Lions suffered their fourth defeat of the season Saturday, dropping a rescheduled away match to Villanova 2-1.
In a showdown between seven-time national champions, Stanford swept the Nittany Lions 25-23, 25-20, 25-20 in Big Ten/Pac-12 Challenge action.
Cuylle committed to Penn State on June 5, but he must forfeit his NCAA eligibility after signing with Windsor on Thursday.
Aurelia Meijer finished the game with four points, and two other Nittany Lions scored their first career goals in a dominant home victory.
Shea Moyer, Kristin Schnurr, Charlotte Williams, and Kerry Abello scored for the Nittany Lions in their decisive victory over the Orange.
Zürich native Kim Dubs has played the most minutes of any Penn State freshman this season, scoring her first collegiate goal against Duquesne.