A strong second period wasn't enough for Penn State to extend its Big Ten Tournament hopes after a late goal from Minnesota.
Gretchen Gilmore netted the game-winner early in overtime after crawling back from a 4-0 deficit.
Matt Traynor scored seven times on Penn State's way to victory.
The Nittany Lions' losing streak increased to five games in the sweep.
"We were playing on our toes -- on our heels, I should say, versus playing with pace and playing fearless, like we did the first round against them."
UCLA is now 2-0 against Penn State and has an all-time record of 35-8-1.