It was the team's fourth overtime loss of the season and second-straight loss.
The Nittany Lions failed to answer Villanova's two late goals as they lost their first game of the season.
Penn State's depth didn't show up against Saint Francis, but John Kerr led the momentum to spark the 3-2 comeback victory.
The Bucknell Bison had just 11 shots on goal as the Nittany Lions defense held them back all game long.
Freshman Kanye Clary set a new career high with 17 points, but the Nittany Lions were unable to sneak out of College Park with a win.
Kiara Zanon, Tessa Janecke, and Izzy Heminger all received the weekly nod after a dominant series at Syracuse.