Designated hitter Josh Spiegel led the way offensively for the Nittany Lions, driving home four runs while going 4-for-5 at the plate.
Penn State's Saturday loss leaves it alone at the bottom of the Big Ten standings.
Sessoms will have one year of eligibility remaining as he joins MEAC-contending Coppin State.
Some sloppy fielding and underwhelming pitching led to Penn State's downfall Friday night against the Boilermakers.
Penn State's bats came alive this weekend in its series win.
From May 6 to 8, the women's club water polo team will have a chance to prove their strength and secure the national title.