Between February 7 and 13, the department administered 2,282 tests, resulting in 16 new positive tests and one pending result.
O'Keefe currently sits at seventh all-time in NCAA history with 192 career goals to his name.
The Nittany Lions will get a chance for revenge against the Cornhuskers next Tuesday.
New head coach Clarisa Crowell has a big challenge ahead of her in her first year as head coach
"We want to win the Big Ten and then compete for a national championship. That is always our goal."
The four-team tournament will be played from November 26 to 27 at Northwest Florida State College.