The Nittany Lions were aided by three touchdown passes from Drew Allar, as well as two punt return touchdowns from Daequan Hardy.
Tight end Khalil Dinkins and offensive lineman JB Nelson were listed as out.
Saturday's Homecoming game should be a rainy, windy affair.
UMass is 1-6 this season, with its lone win being a 41-30 victory over New Mexico State.
The Nittany Lions have dominated in the secondary, holding some of the best passing statistics in the nation.
Our staffers unanimously believe Penn State will win its first game after the bye week.