The senior appeared in just three games during the 2020 season.
Both Wisconsin and Penn State said they'd work with the Big Ten to "identify rescheduling options" and potentially make the game up later in the season.
Flowers is the third four-star wide receiver to join Penn State's talented recruiting class of 2022.
After posting a mediocre 3-5 record in Phase I, the Nittany Lions are determined to improve and become a contender in the second half of the season.