Two Friends are best known for their hour-long "Big Bootie" mixes and collaborations with artists.
This is the Nittany Lions' fourth noon kick of the year and third time on Big Noon Kickoff.
The matchup needs a prime-time slot.
The game will serve as the Nittany Lions' Helmet Stripe game.
The Nittany Lions also appeared on Big Noon Kickoff against West Virginia.
The matchup against UCLA will be the first time the Nittany Lions face one of the Big Ten's newest additions.