Tambroni aims to see Jack Posey and Kevin Parnham back in action within the next three weeks.
Penn State is now the third-ranked Big Ten team.
Kyle Lehman had one assist and three shots against Ohio State.
Penn State boasts the longest winning streak in the country with seven straight victories since week one.
The Nittany Lions are the top-ranked Big Ten team in the USILA and Inside Lacrosse polls.
The Nittany Lions came flying out of the gates and secured a 5-0 lead in the first quarter and never looked back.