This will be the second time this season the Nittany Lions play on ABC.
Rhule compiled an 11-27 record with the Panthers since taking over as their head coach in January 2020.
James Franklin didn't give a reason as to why Vilbert will be unavailable.
From the rainy conditions to beer sales in Beaver Stadium, it was a chaotic Saturday in State College.
State College police alerted the community via social media that the male has returned on his own.
Penn State boasts a 14-5 over the Wildcats and have outscored them 571-352 in the all-time series.