Anna Simon opened the scoring early, and second-half goals by Simon and Jemma Punch gave Penn State the win.
Many analysts believe Penn State will take on Wake Forest in the Orange Bowl.
This is the second time this season Clifford has earned the honor and the fourth time in his career.
Penn State has recorded back-to-back shutout wins for the second time this season.
After back-to-back overtime games, Penn State picked a big shutout win Friday night.
Parsons earned the award after his dominant two-sack performance in the Cowboys' 22-10 win over the Los Angeles Rams