Coupled with Tuesday’s dashboard update, Penn State reported 289 new cases at University Park this week.
This brings Penn State Athletics' cumulative positive tests to 151 since testing began earlier this summer.
Birx stressed the importance of increased testing and mitigating the coronavirus' "silent spread" Wednesday.
According to the dashboard, 403 student cases remain active at University Park, while 2,952 are inactive.
Coupled with Tuesday’s dashboard update, Penn State has reported 481 new student cases at University Park this week.
The center is currently treating 13 coronavirus-positive inpatients aged 33 to 96.