Alexis Horst scored two goals off the bench, adding to goals scored by Moira Putsch and Anna Simon.
Penn State dominated the visiting Buckeyes on Sunday behind goals from Molloy, Curran, and Kenney.
Jonni Parker set a new career high with 17 kills Saturday night, while Bryanna Weiskircher dished out 48 assists.
Freshmen Allyson Cathey and Serena Gray both set new career highs in kills for the Nittany Lions with 13 and 11, respectively.
Nia Reed's nine kills led the way offensively for the Nittany Lions in their sweep of Howard Friday night in Washington, D.C.
Kim Dubs scored the game-winning goal for the Nittany Lions in the 32nd minute of Friday night's Big Ten opener at Jeffrey Field.