Nelson missed the majority of the game against Northwestern and was absent against UMass.
The matchup between the two top-10 teams will be televised on FOX.
With the Nittany Lions officially bowl-eligible, we asked our staffers where they'd like to see Penn State end up this postseason.
"We just have to cross every T, dot every I, and be as prepared as we can when we get on that plane."
Drink whatever you have whenever you hear any Ohio banter. Beat the Buckeyes!
The Nittany Lions' best cornerback Kalen King will most likely be tasked with guarding wide receiver Marvin Harrison Jr. come Saturday.