Ryan DeSanto tossed seven complete innings for Penn State as the Nittany Lions completed a late comeback win.
The game will be played at Mohegan Sun Arena in Connecticut.
Doggie's is guaranteed a spot through to the Final Four, while Cafe, Pickle's, and Antifragile will duke it out for the other three spots.
Rain is expected in Happy Valley Friday afternoon.
The apparent departure from the programs comes a few months after Nelson announced his intention to return in January.
"We're sweating, but we're just happy to be out here."
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