Sean Clifford, Chris Godwin, and Pat Freiermuth all made an impact for their teams in the playoffs.
"The bottom line is that it was a great game and that was a great week for the Indiana Hoosiers."
The game also has an over-under set at 42.5 points.
Despite being without head coach Jim Harbaugh, the Wolverines put up 231 rushing yards against the Nittany Lions.
The Nittany Lions are on FOX for the fourth time this season.