The Nittany Lions outshot Notre Dame 35-28 but couldn't beat Irish goaltender Ryan Bischel.
The Nittany Lions stayed in this game despite an ugly first half, but their late-game shots weren't enough to head home with a win.
Cael Sanderson's group used two pins and a couple of clutch victories to roll to a 32-7 victory over the Buckeyes.
Two sacks from Jesse Luketa and a 75-yard punt from Jordan Stout highlighted a strong Senior Bowl week from Penn State's four representatives.
Syracuse goaltender Arielle DeSmet had standout performances in both games, making life difficult for Penn State.
The Nittany Lions' offense overpowered the visiting Leopards down the stretch Saturday afternoon.