Peter Mangione scored a last-minute goal, but the captain's efforts weren't enough to secure a comeback win.
Owusu joins the Nittany Lions as a transfer from Virginia Tech.
Between the posts, Asman recorded four saves against the Boilermakers and 11 against a stout Wildcat offense.
McSorley was waived by the New England Patriots prior to the 2023 season.
Kirwan scored a goal against both Clarkson and St. Lawrence over the weekend.
Isaac's stat line this season is impressive, totaling 12 tackles and five sacks through the Nittany Lions' first five games this season.