The Nittany Lions last claimed a conference title wearing white in 2005.
Faccia Luna has been temporarily closed after multiple people reported becoming ill.
Jess Mruzik headlined the group as a unanimous selection.
This marks the fifth time Gladieux has earned first-team All-Region recognition.
Penn State will play seven games at home and five away in 2025.
The freshman racked up 11.05 assists per set this season.