Though Penn State pulled away in the second half, the team definitely didn't put together a perfect performance against the Bulls.
Finegan broke his tibia and fibula in the third quarter of Buffalo's 45-13 defeat to Penn State on Saturday night.
The Nittany Lions are favored to beat Pitt for the third consecutive season.
The Nittany Lions moved up two spots in this week's AP Top 25 poll.
Freiermuth made eight catches for 99 yards and added a pair of touchdowns in Penn State's big victory over Buffalo.
Reid's 36-yard pick-six of Matt Myers gave Penn State a lead it wouldn't relinquish for the remainder of Saturday's 45-13 win over Buffalo.