The Nittany Lions hold the biggest disparity in earned runs and runs allowed in the Big Ten.
The Nittany Lions tagged 13 hits on Saturday, but only managed three in the series decider.
The Nittany Lions trailed by six runs in the second inning.
Molinaro's blast marks the 30th of his Penn State career.
Bryce Molinaro had a triple and a home run in the second inning.
"I wanted my sport to be simple. All you would need is a ball, two goals, and a field."