Penn State couldn't complete the comeback attempt as the Lady Lions drop their 12th Big Ten contest of the season.
Matt Traynor passed 100 career points with four goals and two assists on the day.
The Nittany Liosn finished opening weekend with one win over Kennesaw State.
The Nittany Lions blew the game open in the third period.
Penn State get its first win of the season after starting 0-7.
UCLA closed the game on a 34-15 run.