The Lady Lions dropped their final non-conference game of the year 68-65 to Kansas on Sunday afternoon.
The top two seeds will meet Sunday night for a spot in the semifinals.
Baldwin notched his 700th career assist in the first half and now holds Penn State's single-game assist record with 16.
The Nittany Lions take on Creighton at 8:30 p.m. on Sunday, December 15.
The Nittany Lions advanced to the quarterfinals after falling to do so in their last two NCAA Tournament appearances.
The Nittany Lions will play 26 games at home.