Simon Mack became the fourth-straight defenseman to lead the Nittany Lions.
Penn State fell to the Spartans in a top-ten match for only its second loss of the season.
The Nittany Lions move to 10-1 with the Sunday afternoon win.
After a sluggish start, Phia Gladieux scored a brace to win the Route 45 Rivalry.
The victory ended a three-game losing streak for the Nittany Lions.
The Nittany Lions rebounded from their previous outing, claiming victory from the Dukes in straight sets on Friday.