Shay Ciezki dominated the fourth quarter, and her 17 points stole the show and secured victory for Penn State.
With the win, the Nittany Lions advance to their first Elite Eight since 2018.
The Nittany Lion backline has yet to concede a goal in tournament play so far.
The 5-3 victory marks Penn State's first victory in Yost Ice Arena since 2019 and first conference win this campaign.
The Nittany Lions took their final home game in dominant fashion.
Erica Dambach clinched her seventh consecutive NCAA Tournament Sweet Sixteen berth, which is tied for the longest active streak in Division I women's soccer.