Julie Gough scored two goals in the victory.
The Nittany Lions move up two spots after splitting its series against No. 1 Minnesota.
Project 44 is an organization that focuses on helping people find bone marrow matches.
The Nittany Lions held their opponent to 15 shots in their ninth win of the season.
In an action-packed first game of the NCAA tournament, goals from Payton Linnehan, Penelope Hocking, Cori Dyke, and Kate Wiesner propelled the Nittany Lions to the second round.
Penn State will play in its first semifinal game since 2007.