A 7-0 run propelled the Nittany Lions to victory despite originally facing a 4-0 deficit in the second quarter.
Evan Barratt's three-point night helped the Nittany Lions punch their ticket to the next round of the Big Ten tournament, where they'll face No. 1 seed Notre Dame in South Bend next Saturday.
The Nittany Lions didn't have enough energy left in the second half of this semifinal, as Purdue made 54 percent of its shots compared to Penn State's 34 percent performance.
Madison Carter and Maria Auth combined for nine goals Saturday at Panzer Stadium, but it wasn't enough to hold off a late charge from the Greyhounds.
After two rounds, Penn State sits in second place with 82.5 points, just behind first-place Ohio State's 85.5 points.
The fifth-year senior has been a key player for the Nittany Lions in the absence of Mike Watkins.