Sean Spencer's Wild Dogs have now accumulated 25 sacks on the season, securing 25 turkeys to be donated to the State College Food Bank at Thanksgiving.
Penn State's last trip to Ann Arbor also kicked off in the middle afternoon.
Trace McSorley failed to throw for a passing touchdown against Indiana for the first time as Penn State's starting quarterback.
Penn State's wideouts left a lot to be desired, but its front seven had a strong game in Bloomington.
The Nittany Lions moved up one spot following their 33-28 victory over Indiana on Saturday.
Jonathan Sutherland's forced fumble on an Indiana punt return early in the fourth quarter proved essential to Penn State's 33-28 win.