The Nittany Lions moved up two spots after beating Purdue 35-7 on Saturday afternoon.
Penn State Athletics hasn't confirmed a kickoff time or network assignment yet, but Fowler said "we'll be there" for the White Out game while tweeting back and forth with a Penn State fan.
The Nittany Lions and Hawkeyes' week 7 contest will be broadcast nationally on ABC.
Wade made a Penn State-leading 11 tackles and seemed to be everywhere on Saturday afternoon at Beaver Stadium.
Cain led the Nittany Lions with 105 rushing yards and provided a much-needed spark to an otherwise pedestrian second-half offense.
Penn State sacked Purdue quarterback Jack Plummer 10 times and held the Boilermakers to -19 rushing yards on Saturday.